TWiV 456: Be careful of canons

Brianne joins the TWiVMasters to explain how mutations in genes encoding RNA polymerase III predispose children to severe varicella, and detection of an RNA virus by a DNA sensor.

Hosts: Vincent Racaniello and Rich Condit

Guest: Brianne Barker

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This episode is brought to you by the Defense Threat Reduction Agency. Part of the U.S. Department of Defense, the Agency’s Chemical and Biological Technologies Department hosts the 2017 Chemical and Biological Defense Science & Technology Conference to exchange information on the latest and most dynamic developments for countering chemical and biological weapons of mass destruction. Find out more at

Weekly Science Picks

Brianne – Up-Goer Five Challenge (related to Thing Explainer) Rich – The Farthest: Voyager in Space and Vipassana Momma: Science Vincent – Episode of Revisionist History: The Basement Tapes

Listener Pick

Jennie – What Piece of Lab Equipment Are You?

Intro music is by Ronald Jenkees.

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Author: Vincent Racaniello
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